Through dynamic simulation of the cross-hinge four-bar mechanism, it is found the primary reason for unbalance of the mechanism results from the unequal swing angle of driving link and driven Insulated Beverage Containers/Dispensers link.To simplify analysis and calculation, a spatial switching approach was proposed to switch nonlinear problem into
Glucocorticoids Regulate Circadian Rhythm of Innate and Adaptive Immunity
Animals have evolved circadian rhythms to adapt to the 24-h day-night cycle.Circadian rhythms are controlled by molecular clocks in the brain and periphery, which is driven by clock genes.The circadian rhythm is propagated from the brain to the periphery by nerves and hormones.Glucocorticoids (GCs) are a class of steroid hormones produced by the ad
An Approximate Regularized ML Approach to Censor Outliers in Gaussian Radar Data
This paper considers the problem of censoring outliers from the Insulated Beverage Containers/Dispensers secondary dataset in a radar scenario where the sample support is limited.To this end, the generalized regularized likelihood function (GRLF) criterion is used and the corresponding regularized maximum likelihood (RML) estimate of the outlier su
A longitudinal study of attitudes toward evolution among undergraduates who are members of the Church of Jesus Christ of Latter-day Saints.
Polling data reveal a decades-long residual rejection of evolution in the United States, based on perceived religious conflict.Similarly, a strong creationist movement has been documented internationally, including in the Muslim world.Members of the Church of Jesus Christ of Latter-day Saints (LDS, Mormon), a generally conservative denomination, ha
NRF2 in age-related musculoskeletal diseases: Role and treatment prospects
The NRF2 pathway is a metabolic- and redox-sensitive signaling axis in which the transcription factor controls the expression of a multitude of genes that enable cells to survive environmental stressors, such as oxidative stress, mainly by inducing the expression of cytoprotective genes.Basal NRF2 levels are maintained under normal physiological co